Sh-Oligopeptide-1
PRODUCT OUTLINE
sh-Oligopeptide-1 is a bio-identical peptide inspired by epidermal growth factor (EGF).
Developed using advanced recombinant protein expression in E. coli and purified through high-performance chromatographic methods, it delivers exceptional purity, stability, and consistency for science-backed skincare formulations.
Designed for cosmetic applications, this peptide helps support the skin’s natural renewal environment, contributing to a smoother, more luminous, and revitalised appearance. With continued use, it helps enhance the look of elasticity and luminosity, promoting a refined texture and a youthful-looking radiance
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Figure 1. Effect of sh-Oligopeptide-1 (20250123-EGF) on HaCaT keratinocyte cell proliferation, tested over 48 hours.
This bar graph illustrates the effect of sh-Oligopeptide-1 on the proliferation of HaCaT keratinocyte cells after 48 hours. The y-axis represents the absorbance value measured at 570 nm, indicating relative cell proliferation. The x-axis presents the tested samples; a negative control of HaCaT cells in the absence of sh-Oligopeptide-1, and HaCaT cells treated with 2.5 ng/mL of sh-Oligopeptide-1. The results demonstrates a significant improvement in HaCaT cell proliferation when in the presence of sh-Oligopeptide-1.
Sh-Polypeptide-1
PRODUCT OUTLINE
Sh-Polypeptide-1 is a potent peptide that stimulates cell proliferation and tissue regeneration across various cell types, including dermal fibroblasts, neuronal cells, endothelial cells, keratinocytes, chondrocytes, myoblasts, and osteoblasts.
In cosmetic formulations, Sh-P-1 is known to enhance skin elasticity, reduces wrinkles, and supports hair growth while helping prevent hair decolorisation.
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Developed using advanced recombinant protein expression in E. coli and purified through high-performance chromatographic methods, it delivers exceptional purity, stability, and consistency for science-backed skincare formulations.
Figure 1. Effect of 100 ng/mL of sh-Polypeptide-1 (20241018-FGF2) on NIH-3T3 cell proliferation, tested over 48 hours.
This bar graph illustrates the effect of sh-Polypeptide-1 on NIH-3T3 cell proliferation measured at 48 hours (T48) using an MTT assay. The y-axis represents the absorbance at 570 nm, which is indicative of cell proliferation, while the x-axis shows the sh-Polypeptide-1 samples that were compared. Each sample was tested at a concentration of 100 ng/mL. Immobazyme's sh-Polypeptide-1 results in significantly higher absorbance at 570 nm compared to Competitor A, suggesting greater cell proliferation.
Sh-Oligopeptide-2
PRODUCT OUTLINE
sh-Oligopeptide-2 is a bio-identical peptide inspired by insulin-like growth factor-1 (IGF-1), produced using advanced recombinant protein expression and purified through high-performance chromatographic processes to ensure exceptional purity, consistency, and formulation reliability.
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Engineered as a stabilised fusion peptide, Immobazyme’s sh-Polypeptide-2 offers enhanced solubility and formulation compatibility, allowing seamless incorporation into modern cosmetic and personal care systems.
Figure 2. Effect of SH-O-2 on MCF-7 (3000 cells/well) proliferation over 7 days.
An MTT assay shows a sigmoidal dose–response curve, with cell proliferation increasing as SH-O-2 concentration rises. The X-axis (SH-O-2 concentration, ng/mL) is displayed on a logarithmic scale, while the Y-axis represents absorbance at 570 nm (background-subtracted), corresponding to proliferation relative to untreated controls. The ECâ‚…â‚€, where 50% of maximal proliferation is achieved, is approximately 55 ng/mL. At low concentrations, proliferation remains near baseline, increases sharply around the ECâ‚…â‚€, and plateaus at higher concentrations, indicating saturation. This demonstrates the dose-dependent effectiveness of SH-O-2 in stimulating MCF-7 cell growth.
Sh-Polypeptide-22
PRODUCT OUTLINE
sh-Polypeptide-22 is a bio-identical peptide inspired by transforming growth factor beta-1 (TGF-β1), produced using advanced recombinant protein expression and purified through high-performance chromatographic processes.
Immobazyme’s sh-Polypeptide-22 offers enhanced solubility and compatibility across a wide range of cosmetic formulation systems, enabling seamless integration into modern skincare and personal care products.
Designed exclusively for cosmetic use, sh-Polypeptide-22 helps support the skin’s natural extracellular environment, contributing to a smoother, more refined skin appearance.
