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An interview with Soyama Nyangwa.


Immobazyme's Molecular Biologist, Soyama Nyangwa
Meet Soyama Nyangwa, Immobazyme's Molecular Biologist

We sat down with Soyama to discuss his PhD, passions, and aspirations for Immobazyme and beyond.


Could you give us an overview of your PhD research?

Certainly! Interferon gamma (IFN-γ) is a critical cytokine with essential roles in the host immune system. Post-translational modifications and truncations of IFN-γ may significantly impact its function and interactions with immune cells. In my PhD project, we aimed to investigate the effects of these modifications on the host immune system by utilizing THP-1 derived macrophages as a model system. Recombinant proteins expressing modified forms of IFN-γ will be generated using E. coli and HEK 293 cells to study the resulting immune responses.


The project involved characterising the structural integrity using biophysical methods and also biological activities of the different IFN-γ variants in terms of their ability to activate macrophages and modulate immune responses.


The findings from this study provided valuable insights into how post-translational modifications and truncations impact the function of IFN-γ and its potential therapeutic applications in immune-related diseases. Ultimately, this research contributes to a better understanding of the molecular mechanisms underlying the immune responses mediated by IFN-γ and aid in the development of novel immunotherapies.


What are your aspirations within Immobazyme and the biotech industry?

My primary goal is to contribute to the development of technologies and therapies that have the potential to positively impact human health and the world we live in. I am passionate about translational research, where scientific discoveries are translated into practical applications, and I aspire to be part of a team that brings innovative solutions to market.


In the long term, I hope to grow with the company and advance in my career to eventually lead my own projects and team of research scientists at a directorial level. I aim to cultivate a strong network of collaborators and mentors within the company to acquire new skills and knowledge that will enable me to make significant contributions to the field of biotechnology.


Additionally, I am interested in pursuing passion projects that involve exploring emerging technologies like gene editing, personalized medicine, and regenerative medicine. I believe that these areas have the potential to revolutionize healthcare and improve patient outcomes, and I am eager to be involved in research that pushes the boundaries of what is possible in biotechnology.


When we’re not at work, where can I find you, and what will you be doing?

When I'm in the labs, you can find me soaking up the sun at the beach or exploring different seaside towns. I love spending time with good company, whether it's hosting game nights or just hanging out and catching up over a cold one. And don't be surprised if you see me snapping pictures everywhere - I have a love for photography, but I'm still saving up for a proper camera.


Closing Thoughts

Soyama has made a significant impact at Immobazyme, both through his innovative work and his vibrant personality.

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