Dextranase is an enzyme that catalyzes the hydrolysis of dextran, a complex polysaccharide composed of glucose units linked together through α-1,6-glycosidic bonds. This enzyme specifically targets the α-1,6-glycosidic linkages present in dextran, breaking them down into smaller fragments. Dextranases are classified as glycoside hydrolases and are widely found in various microorganisms, including bacteria and fungi.

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The primary function of dextranase is to degrade dextran, which is a sticky and viscous polysaccharide. Dextran is produced by certain bacteria, such as Leuconostoc and Streptococcus species, and can be found in food products, industrial processes, and dental plaque. In food processing, dextran can lead to undesirable properties such as increased viscosity, poor texture, and reduced shelf life. Therefore, the use of dextranase helps to eliminate or reduce the presence of dextran and its associated negative effects.

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Immobazymes recombinant dextranase is produced in the methylotrophic yeast, Pichia pastoris and purified using immobilized metal ion affinity chromatography.